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What elements should be considered in the selection, purchase and acceptance of reference substances?

2020-03-30 11:06:25

The standard substances purchased by users are often of high concentration and cannot be used directly, so the quality control of these processes should be done, and the containers and diluents used in the preparation of standard substances dilution also need to be paid attention to. Below, we will share with you what elements should be considered when selecting, purchasing and accepting standard substances.


What elements should be considered when selecting, purchasing and accepting standard substances:


1, the type of characteristic quantity and setting method: some standard substances may only apply to a specific method or exclusive field of application, the value of some standard substances have special provisions, such as the value of crystal water, should be noted in the certificate to prevent misselection and misuse.


2, the characteristic quantity level: the characteristic quantity level of the standard material should match the level of the daily measurement sample.


3, acceptable level of uncertainty: the level of uncertainty related to the characteristic quantity of the standard material should be matched with the correct variation limit requirements of precision in daily measurement.


4, matrix and possible interference: When the reference material is used to carry out method confirmation, quality control and calibration of some measurement methods with more serious matrix effects, the matrix should be as close as possible to the daily measurement sample matrix.


5, form: the standard material can be prepared into different forms, such as freeze-dried and frozen samples, the different preparation methods may lead to the same characteristics in the standard material and the real sample behavior difference, resulting in interchangeability problems, should be fully investigated before purchase.


6, the minimum sampling amount: as long as the minimum sampling amount specified in the standard material certificate, the sampling amount used for measurement should not be less than the minimum sampling amount, so the purchase should consider whether the minimum sampling amount can meet the requirements of the measurement method.


7, dosage: The amount of standard material purchased should be sufficient to meet the application of the entire experimental plan, including the preparation sample considered as necessary.


8, stability: before the purchase should confirm the validity period of the purchased batch of standard material, to avoid expiration of the use of the standard material, after receiving the standard material should first check the certificate to confirm that the transport conditions of the standard material meet the requirements, and then check whether the variety, quantity, etc., is consistent with the purchase requirements; Whether the packaging and appearance are normal, and whether the logo is clear and complete; Certificate or not: whether it is within the validity period of the certificate declaration, etc., after checking, immediately save according to the storage conditions specified in the certificate if there is any problem. Should promptly contact the development or distribution unit.


The above content is the selection, purchase and acceptance of the standard material should be considered when the elements of the introduction, the user after receiving the standard material need to check whether the number of varieties and other consistent with the purchase, the identification is clear and complete, there is no certificate, whether the product is within the validity range, after the completion of the check need to be stored in accordance with the storage conditions given by the certificate.

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